The artist has donated the full amount of his twenty-five thousand pound honor prize money to the trust for venues, which works to preserve the Britain's small concert spaces.
The star was presented with the cheque on 16 October as his new release his work was named the outstanding release of the past year.
The musician has opted to hand the money over to the Music Venues Trust, in appreciation of the vital role local spots had in his early career.
"As an artist would not have achieved this success if it hadn't been for all the gigs I performed around the area, and further afield, when I was just getting going," stated Sam Fender. "These spaces are iconic, but they are in difficulty."
From early 2023 onward, at least 150 of these locations have shut down – approximately one-sixth of the entire UK sector.
In the last year, well-known musicians like Pulp, Coldplay, Katy Perry and Sheeran have all aided the trust in its initiatives to help venues survive, by adding a minor surcharge to their ticket costs, which supports smaller concert halls.
He also joined in, generating in excess of £100,000 on his 2024 arena tour to support numerous small stages across the UK.
The donation supported spaces that were confronting potential shutdown due to issues stemming from floods, blazes and personal losses, as well as licensing issues, court cases and sound issues.
Additional spaces received funding support in modernizing facilities and sound and lighting systems that directly benefitted musicians and concertgoers.
"The notion that money from concerts in major spaces backs the local stages, where it begins for musicians like me, is just common sense," Sam Fender has commented.
He is among several artists to contribute his Mercury Prize winnings to good deeds.
When the band received the award in 1996 for their album Different Class, lead singer Cocker declared that the band would donate their winnings to the organization the charity.
In 2002, musician Ms Dynamite shared her bounty between a few organizations, like the NSPCC and a charity for Sickle Cell.
"I also donated a £1,000 to my local community centre, to their gymnastics program, because I practiced gymnastics when I was a child and they needed better apparatus," the artist told the media.
Two years ago, they donated their prize money to the youth organization that nurtured their band, in addition to other independent music bodies.
Additionally the 1994 recipients M People donated their winnings to a charity for MS after a friend was found to have the condition.
"The victory was ample," stated vocalist the singer. "The cash was the bonus but we could do without the bonus, because we had the honor. So our victory affected another person's life."
Last week, the MVT shared it had saved two small stages in the South East, by placing them under community ownership.
The first in Southampton and the second in that location were purchased under the public acquisition program, which is funded by Arts Council England and supporters who acquire "stakes" in the venues.